Tubulointerstitial disorders are clinically distinct illnesses that share tubular and interstitial injury. In severe and long-term situations, the whole kidney may become complex, resulting in glomerular dysfunction and possibly renal failure.
Tubulointerstitial nephritis is a primary injury to the renal tubules and interstitium that results in decreased renal function. The critical type is most commonly caused by adverse medication reactions or infections. The chronic disease type is caused by a variety of factors, including hereditary or metabolic disorders, obstructive uropathy, and longterm exposure to environmental pollutants or certain medications and herbs. A history and urinalysis are used to make a diagnosis, which is typically confirmed by a biopsy. Treatment and prognosis differ depending on the aetiology and probable reversibility of the illness at the time of diagnosis.
- Acute Tubulointerstitial Nephritis
- Analgesic Nephropathy