The most common or conventional arrangement of the renal arterial vasculature begins with a single artery that splits into anterior and posterior branches. There are no significant collateral arteries feeding the same circulatory bed as the renal arteries. The distal arterioles terminate at the junction of the anterior and posterior supply zones. This region, known as the Hytrol or Broder line, is generally positioned along the poster lateral side of the Kidney and is the safest site to acquire Kidney tissue samples for untargeted biopsies. Medical imaging investigations do not show this region of relative hypovascularization.
The native kidney is normally found in the retroperitoneal region. To prevent difficulties, biopsies of native kidneys should be conducted so that the needle only penetrates this area. Inserting a needle into the Kidney's central hilum, which contains the major arteries, veins, and calyces, should also be avoided. Because the majority of the glomeruli utilised for assessment are found in the renal cortex, sampling the renal cortex rather than the renal marrow is often recommended for non-targeted biopsies.