Many disorders impair kidney function by attacking the glomeruli, the small units within the kidney that clear the blood. Glomerular illnesses are a group of ailments that have a range of hereditary and environmental origins, but they may be divided into two groups.
Glomerular disorders cause glomeruli damage, causing protein and occasionally red blood cells to leak into the urine. A glomerular illness can also interfere with the removal of waste products by the kidney, causing them to accumulate in the blood. Furthermore, loss of blood proteins such as albumin in urine might result in a decrease in their amount in the circulation. Albumin behaves like a sponge in normal blood, pulling excess fluid from the body into the circulation, where it remains until the kidneys eliminate it. However, when albumin leaks into the urine, the blood loses its ability to absorb excess fluid from the body. Fluid can build up outside the circulatory system and produce edoema in the face, hands, feet, or ankles.