Muhammad Awais
University of Rochester Medical Center
Biography:
Dr Muhammad Awais is a young nephrology physician. He has several poster presentations, clinical audits to his credit. In addition to this he has completed medical training with college of physicians and surgeons in Pakistan. He believes in research as the modality to move forward. Dr Awais particular interest is in chronic kidney diseases and general nephrology.
Abstract:
Over the last two years, our hospital has admitted three dialysis patients with warfarin induced calciphylaxis and their hospital course was noted and is discussed in this case series report.
Three cases of calciphylaxis were admitted from 2020-2022 in the nephrology department of PSMMC. All 3 patients were registered chronic dialysis patients of PSMMC. These cases were carefully studied while they were on the standard treatment. The combination of clinical feature and skin biopsy was used to diagnose the cases. All three patients were on warfarin for atrial fibrillation.
Results
The mean age of this series was 57, with an average BMI of 39. One of them was on peritoneal dialysis where as other 2 patients were on hemodialysis. All three patients were on warfarin for atrial fibrillation, two of them had skin lesion in abdomen whereas the third patient had lesion on thigh. All of them were diabetic and female. Two third of them had hyperparathyriod bone disease. All of them had calcium phosphate product above 5.7 mg/dl despite adequate premorbid medical measures. 2 out of 3 died of gram negative sepsis. The patient who survived had no evidence of sepsis and skin lesion showed growth of skin type flora only. All Patients under went surgical debridement. The average hospital stay was 120 days.