23^rd International Conference on
Nephrology and Urology

Biography:

The main auhor is an Internal Medicine Specialist who completed her residency training and research at Notre Dame de Chartres Hospital. She is set to embark her fellowship journey to specialize in Nephrology. Research has been a passion since her undergraduate course in Nursing with previous works presented internationally, and she continues to hope for future works of publication and presentation.

Abstract:

World Health Organization declared COVID-19 as a Global Pandemic last 2020, often associated with respiratory failure. Sepsis is a dysregulated host response to infection that leads to acute organ dysfunction. Hemoperfusion is an extracorporeal blood purification method commonly used in sepsis, which proposed to improve outcomes by removing inflammatory mediators via highly biocompatible sorbents and microporous resins. Inflammatory cytokines with COVID-19 patients are high, therefore, hemoperfusion may improve patients’ condition. The study is to determine the demographic profile and outcomes of Hemoperfusion on Sepsis and COVID-19 Patients. Methods: An observational cross-sectional study design wherein Descriptive statistics and Inferential mode of analysis were used. Results: 66 patients were studied. A mean age of 63, predominantly males were found. The most common co-morbidity was Hypertension. Among demographic profiles, there were no significant association with COVID-19 and Sepsis.  Remarkably, there is a significant association between Sepsis and COVID-19 with regards to initiating Hemoperfusion and their outcome. Improvement and Mortality after Hemoperfusion were both at 50% respectively. Critically Ill COVID-19 patients had the highest mortality rates, while higher survival rate was noted for COVID-19 Severe and Non-COVID Septic patients. There was significant Improvement after Hemoperfusion with regards to Creatinine, Ferritin, CRP and IL-6 levels in Severe COVID 19 and Sepsis patients. Ferritin, D-Dimer, LDH markers, the need for mechanical ventilation were found to have no significance to the entire population of the study. Conclusion: Hemoperfusion has a noteworthy outcome on Septic and COVID-19 Severe patients, aiding in clinical improvement. Majority of the inflammatory markers were noted to improve. Hemoperfusion had no significant correlation for age, gender, co-morbidities, and need for mechanical ventilation.

Biography:

Dr Muhammad Awais is a young nephrology physician. He has several poster presentations, clinical audits to his credit. In addition to this he has completed medical training with college of physicians and surgeons in Pakistan. He believes in research as the modality to move forward. Dr Awais particular interest is in chronic kidney diseases and general nephrology. 

Abstract:

Over the last two years, our hospital has admitted three dialysis patients with warfarin induced calciphylaxis and their hospital course was noted and is discussed in this case series report.

Three cases of calciphylaxis were admitted from 2020-2022 in the nephrology department of PSMMC. All 3 patients were registered chronic dialysis patients of PSMMC. These cases were carefully studied while they were on the standard treatment. The combination of clinical feature and skin biopsy was used to diagnose the cases. All three patients were on warfarin for atrial fibrillation.
Results
The mean age of this series was 57, with an average BMI of 39. One of them was on peritoneal dialysis where as other 2 patients were on hemodialysis. All three patients were on warfarin for atrial fibrillation, two of them had skin lesion in abdomen whereas the third patient had lesion on thigh. All of them were diabetic and female. Two third of them had hyperparathyriod bone disease. All of them had calcium phosphate product above 5.7 mg/dl despite adequate premorbid medical measures. 2 out of 3 died of gram negative sepsis. The patient who survived had no evidence of sepsis and skin lesion showed growth of skin type flora only. All Patients under went surgical debridement. The average hospital stay was 120 days.

Biography:

Abstract:

CASE REPORT

We hereby report a case of 71 year Female who was previously known to have bronchial asthma, hypertension, ischemic heart disease and was diagnosed as a case of Hepatitis C positive on PCR 30 years before. She was known to have chronic lymphocytic Leukemia in 2012 which converted to marginal zone Lymphoma. She presented with lower limb edema in January 2023 and renal biopsy was done which revealed membranoproliferative glomerulonephritis Type 1. There is no study in the past which has observed the association between all the above mentioned diseases in one patient.

Several Investigations which include Hepatitis C PCR, Computed Tomography Scan of chest abdomen and Renal Biopsy were done for diagnosis and follow up of the progression of disease.

Patient received treatment rutaximab, steroids for treatment of marginal zone lymphoma. There was 50 % improvement of enlarged lymphadenopathy. Patient received ribavirin  treatment for Hepatitis C with high viral load and decompensated liver disease and is under remission. Patient renal biopsy showed global endocapillary projection, mesangial hypercellularity with increased capillary wall thickness. Mild leukocytic infiltrate identified as well as rare intracapillary protein thrombosis. Mild interstitial fibrosis and features consistent with Membranoproliferative Glomerulonephrits Type 1. Patient was given conservative treatment such as antihypertensive medications and diuretics.

Biography:

Dr Kevin Larkin A. Callos is a Filipino physician and has completed his training in Adult-Nephrology fellowship program at Southern Philippines Medical Center Davao City, Philippines. He currently resides in Davao City, Philippines. He is interested in the field of critical care nephrology and plans to pursue a training course. Urinary stones have been an interest during his practice as he encountered a lot of patients with urinary stones and had poor work-ups, dietary advices, medical managements and follow-ups. This study is also being presented for e-poster at the Philippine College of Physicians 53^rd annual congress this May 7-10, 2023. Dr Kevin Larkin A. Callos is a Filipino physician and has completed his training in Adult-Nephrology fellowship program at Southern Philippines Medical Center Davao City, Philippines. He currently resides in Davao City, Philippines. He is interested in the field of critical care nephrology and plans to pursue a training course. Urinary stones have been an interest during his practice as he encountered a lot of patients with urinary stones and had poor work-ups, dietary advices, medical managements and follow-ups. 

Abstract:

Statement of the Problem: Urinary stones are the most common disease of the urinary tract and have a high rate of recurrence. After an initial stone formation, the recurrence rate is as high as 50% at 5 year and 80-90% at 10 years. The prevention of recurrence still remains to be a serious problem for our medical community.  Our main objective was to determine the level of knowledge, attitudes, and practice patterns of Surgeons, Internists, and Family Medicine physicians in Davao City regarding the prevention of recurrent urinary stone formation.

Methodology & Theoretical Orientation: The Study was a prospective descriptive research design. A questionnaire based on a validated study on current best practice guidelines for the management of recurrent kidney stones was used and distributed via online Google form. The questions covered 3 domains: knowledge, attitudes, and practice patterns. Demographic data were also collected.

Findings: A total of 180 respondents answered the questionnaire in the allotted timeframe. The study showed that despite respondents’ sufficient knowledge about urinary stone prevention some did not apply this knowledge effectively in clinical practice.

Conclusion & Significance:  Unfortunately, having good knowledge about prevention of urinary stones was not enough to change the behaviour of some respondents in preventing future stone formation. More education and training should definitely be given or addressed to Family Medicine physicians so that they can be at par with standards of Internists and Surgeons. Practice patterns towards prevention of recurrent kidney stones did differ significantly with the Internal Medicine and Surgery specialization in concordance with the guidelines practices in comparison to the Family Medicine specialization. We believe that our study represents a good chance to understand and evaluate the current stone recurrence prevention practices in Davao City.