Ministry of Health & Qol, Mauritius
Title: To explore the effect of corticosteroids on drug-induced acute interstitial nephritis.
Swalay FEDALLY, Nephrologist at Ministry of Health & Qol, Mauritius and reviewer for peer-review European Journal. He was graduated in Nephrology, M.D. from University of Chongqing, China. His research titles are Changes in Metabolism of Calcium and Phosphorus in patients with Renal Insufficiency treated by Hemodialysis, and Improvement of Drug-Associated Acute Interstitial Nephritis by Corticosteroids. He has an interest over writing and reading medical research articles and case studies. His interest is Interventional Nephrology
Acute interstitial nephritis (AIN) is a form of nephritis that affects the renal interstitium, which is an important cause of reversible acute Kidney Injury (AKI). Drug induced AIN is the commonest aetiology and accounts up to 80% of the causes.AIN is always of sudden onset and fast decline in renal function, usually presenting with an acute rise in blood urea nitrogen (BUN) and creatinine (Cr) values.Renal biopsy provides the most definitive means of diagnosis.Because of its role as anti-inflammatory, inhibition of immune, anti-allergy and prevention of fibrosis, corticosteroids is widely used as a treatment for AIN.