Ministry of Health, Sri Lanka
Title: The burden of chronic kidney disease of uncertain aetiology in Anuradhapura district
Chronic kidney disease of unknown aetiology (CKDu) is known as a problem among paddy farmers of the North Central province. Ministry of Health published a three-tiered epidemiological case definition in 2016 as suspected, probable and confirmed CKDu. Suspected CKDu provides a uniform method to estimate the burden in epidemiological studies and is defined as the presence of essential criteria of eGFR < 60mL/min AND/OR albuminuria >=30mg/g. Among those satisfying essential criteria, those with urine protein:creatinine ratio >2g/g creatinine OR urine albumin:creatinine ratio >0.3g/g creatinine; hypertensive on >2 drugs OR untreated blood pressure >160/100mmHg; history of diabetes OR being on treatment OR capillary random plasma glucose >200mg/dL were excluded.